There is a new study that has come out about the Ketogenic Diet. The ketogenic diet focuses on limited carbs and focusing on high fat and protein. This shifts your body into ketosis. Your body now will use fat as its main energy source compared to glucose. Your body uses glucose as its main energy source when your body isn’t pushed into ketosis.
This study was done on mice, and found there was a right way to do the keto diet and a wrong way. This study focused on the types of fats you eat while being keto. We all know that not all fats are the same. This study was expecting to a keto diet high in MCT (medium chain triglycerides) and Omega-3s is going to help with psoriasis. These fats help when your body is not in ketosis. It has the opposite effect. The fats that we found were anti-inflammatory are making the psoriatic plaque formation worse. LCTs (Long chain trigycerides) did not have any effects on the skin.
“Ketogenic diets supplemented with MCTs not only induce the expression of pro-inflammatory cytokines, but also lead to an accumulation of neutrophils in the skin resulting in a worse clinical appearance of the skin of the mice. Neutrophils are of particular interest since they are known to express a receptor for MCTs and therefore a ketogenic diet containing MCTs may have an impact on other neutrophil-mediated diseases not limited to the skin.”- Co-lead investigator Roland Lang, PhD
What Dr. Lang, PhD is saying, is that the fats we consider anti-inflammatory are pro-inflammatory when your body is in ketosis. The effects so the inflammation the MCT fats are causing are not only going to be seen in the skin. Other inflammatory diseases would be effected as well. This is something that is going to need to have more research.
This study had a very high fat percentage in the diet. This is something that people would not have. So this study should be taken with a grain of salt. If you have psoriasis I would avoid the keto diet until more research can be done.
- Felix Locker, Julia Leitner, Sepideh Aminzadeh-Gohari, Daniela D. Weber, Philippe Sanio, Andreas Koller, René Günther Feichtinger, Richard Weiss, Barbara Kofler, Roland Lang. The Influence of Ketogenic Diets on Psoriasiform-Like Skin Inflammation. Journal of Investigative Dermatology, 2019; DOI: 10.1016/j.jid.2019.07.718